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Weichselbaum, Ralph R.
One or more keywords matched the following items that are connected to Weichselbaum, Ralph R.
Item TypeName
Concept Tumor Cells, Cultured
Concept Cells, Cultured
Academic Article Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
Academic Article Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase.
Academic Article Attenuation of G2-phase cell cycle checkpoint control is associated with increased frequencies of unrejoined chromosome breaks in human tumor cells.
Academic Article C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure.
Academic Article Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231.
Academic Article p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.
Academic Article Footprinting of individual tumors and their variants by constitutive cytokine expression patterns.
Academic Article Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor.
Academic Article The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
Academic Article Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
Academic Article Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis.
Academic Article Down-regulation of cell cycle control genes by ionizing radiation.
Academic Article DNA double-strand break rejoining rates, inherent radiation sensitivity and human tumour response to radiotherapy.
Academic Article Phosphorous metabolite and cell cycle kinetic response of two human squamous cell carcinomas to radiation.
Academic Article Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis.
Academic Article Loss of ceramide production confers resistance to radiation-induced apoptosis.
Academic Article Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors.
Academic Article Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein.
Academic Article The interaction of 5-fluorouracil, hydroxyurea, and radiation in two human head and neck cancer cell lines.
Academic Article Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation.
Academic Article The contribution of DNA ploidy to radiation sensitivity in human tumour cell lines.
Academic Article Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage.
Academic Article Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response.
Academic Article Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation.
Academic Article Combined effects of angiostatin and ionizing radiation in antitumour therapy.
Academic Article Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.
Academic Article Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
Academic Article Angiostatin effects on endothelial cells mediated by ceramide and RhoA.
Academic Article Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Academic Article Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1.
Academic Article NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity.
Academic Article Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.
Academic Article Role for p300 in stabilization of p53 in the response to DNA damage.
Academic Article Cytogenetic evidence of the multistep origin of head and neck squamous cell carcinomas.
Academic Article Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
Academic Article Treatment of head and neck and esophageal xenografts employing Alimta and concurrent ionizing radiation.
Academic Article Enhanced eradication of local and distant tumors by genetically produced interleukin-12 and radiation.
Academic Article Function for p300 and not CBP in the apoptotic response to DNA damage.
Academic Article In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo.
Academic Article Anti-angiogenic cues from vascular basement membrane collagen.
Academic Article Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage.
Academic Article Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis.
Academic Article Quantitative analysis of DNA array autoradiographs.
Academic Article TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene.
Academic Article Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.
Academic Article Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma.
Academic Article Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species.
Academic Article Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
Academic Article Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model.
Academic Article The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma.
Academic Article Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV).
Academic Article Angiostatin potentiates cyclophosphamide treatment of metastatic disease.
Academic Article The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species.
Academic Article Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.
Academic Article Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells.
Academic Article Transcriptional control of viral gene therapy by cisplatin.
Academic Article Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor.
Academic Article STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
Academic Article Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize.
Academic Article Endothelial cells co-cultured with wild-type and dominant/negative p53-transfected glioblastoma cells exhibit differential sensitivity to radiation-induced apoptosis.
Academic Article Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay.
Academic Article Two prostate carcinoma cell lines demonstrate abnormalities in tumor suppressor genes.
Academic Article Cellular and molecular aspects of human tumor radioresistance.
Academic Article Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines.
Academic Article Forphenicinol enhances the antitumor effects of cyclophosphamide in a model of squamous cell carcinoma.
Academic Article p53 gene mutations and abnormal retinoblastoma protein in radiation-induced human sarcomas.
Academic Article Fibroblast radiosensitivity and intraocular fibrovascular proliferation following radiotherapy for bilateral retinoblastoma.
Academic Article Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.
Academic Article Defective reactivation of ultraviolet light-irradiated herpesvirus by a Bloom's syndrome fibroblast strain.
Academic Article Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
Academic Article Sensitivities of NIH/3T3-derived clonal cell lines to ionizing radiation: significance for gene transfer studies.
Academic Article Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
Academic Article Radioresistant tumor cell lines derived from head and neck radiation failures.
Academic Article Southern analysis of human head and neck cancer cells for homologous sequences using yeast gamma repair genes.
Academic Article Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines.
Academic Article Radioresistant tumor cells are present in head and neck carcinomas that recur after radiotherapy.
Academic Article Faster repair of DNA double-strand breaks in radioresistant human tumor cells.
Academic Article Heterogeneous response to X-ray and ultraviolet light irradiations of cultured skin fibroblasts in two families with Gardner's Syndrome.
Academic Article Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells.
Academic Article Long-term culture of human granulocytes and granulocyte progenitor cells.
Academic Article An epidermoid carcinoma cell line derived from hamster 7,12-dimethylbenz[a]anthracene-induced buccal pouch tumors.
Academic Article Lethal effects of 1-beta-D-arabinofuranosylcytosine incorporation into deoxyribonucleic acid during ultraviolet repair.
Academic Article Comutagenic effects of 3-aminobenzamide in Chinese hamster ovary cells.
Academic Article Ionizing radiation stimulates a Grb2-mediated association of the stress-activated protein kinase with phosphatidylinositol 3-kinase.
Academic Article Comparative analysis of the inherent radiosensitivity of ovarian carcinoma.
Academic Article p56/p53lyn tyrosine kinase activation in mammalian cells treated with mitomycin C.
Academic Article Chromosome changes characterizing in vitro response to radiation in human squamous cell carcinoma lines.
Academic Article Effect of Bcl-2 on ionizing radiation and 1-beta-D-arabinofuranosylcytosine-induced internucleosomal DNA fragmentation and cell survival in human myeloid leukemia cells.
Academic Article Deficient recovery from potentially lethal radiation damage in ataxia telengiectasia and xeroderma pigmentosum.
Academic Article Antipain-mediated suppression of sister chromatid exchanges induced by an inhibitor of poly (ADP-ribose) polymerase.
Academic Article Different efficiencies of interaction between 3-aminobenzamide and various monofunctional alkylating agents in the induction of sister chromatid exchanges.
Academic Article An in vitro investigation of x-ray sensitivity in fibroblasts from patients with retinoblastoma.
Academic Article The role of paclitaxel in the treatment of head and neck cancer.
Academic Article X-ray sensitivity of human tumor cells in vitro.
Academic Article Importance of repair of potentially lethal damage in assays of cytotoxic agents.
Academic Article Modification by dexamethasone of radiation response of in vitro cultured cells.
Academic Article Clonal interactions in a human squamous cell carcinoma.
Academic Article Characterization and radiobiologic parameters of medulloblastoma in vitro.
Academic Article Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
Academic Article Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation.
Academic Article Ionizing radiation induces rapid tyrosine phosphorylation of p34cdc2.
Academic Article Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response.
Academic Article Ionizing radiation activates transcription of the EGR1 gene via CArG elements.
Academic Article Repair of fractionated radiation in plateau phase cultures of human tumor cells and human multicellular tumor spheroids.
Academic Article Potentially lethal damage repair (PLDR) in X-irradiated cultures of a normal human diploid fibroblast cell strain.
Academic Article Iodine-125-labelled tamoxifen is differentially cytoxic to cells containing oestrogen receptors.
Academic Article Radioresistance in some human tumor cells conferred in vitro by repair of potentially lethal X-ray damage.
Academic Article X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders.
Academic Article Spatial and temporal control of gene therapy using ionizing radiation.
Academic Article Ketoconazole attenuates radiation-induction of tumor necrosis factor.
Academic Article Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine.
Academic Article Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
Academic Article Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
Academic Article Investigation of the cytotoxic effects of DNA damaging agents on neurofibromatosis cells.
Academic Article Abnormalities of human chromosome 13 and in vitro radiosensitivity; a study of 19 fibroblast strains.
Academic Article Abnormal sensitivity of diploid skin fibroblasts from a family with gardner's syndrome to the lethal effects of X-irradiation, ultraviolet light and mitomycin-C.
Academic Article Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase.
Academic Article Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.
Academic Article The role of intracellular calcium in the cellular response to ionizing radiation.
Academic Article Molecular targets to overcome radioresistance.
Academic Article Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326.
Academic Article Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer.
Academic Article Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus.
Academic Article In vitro cellular radiosensitivity of human malignant tumors.
Academic Article Surfactant sealing of membranes permeabilized by ionizing radiation.
Academic Article Angiostatin induces mitotic cell death of proliferating endothelial cells.
Academic Article Antitumor interaction of short-course endostatin and ionizing radiation.
Academic Article Tumor production of angiostatin is enhanced after exposure to TNF-alpha.
Academic Article Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.
Academic Article Poloxamer 188 prevents acute necrosis of adult skeletal muscle cells following high-dose irradiation.
Academic Article X-ray sensitivity of diploid fibroblasts from patients with hereditary or sporadic retinoblastoma.
Academic Article The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
Academic Article Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
Academic Article Genetic radiotherapy overcomes tumor resistance to cytotoxic agents.
Academic Article p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
Academic Article A link between calcitriol and bone resorption.
Academic Article Effects of dexamethasone and cortisone with x-ray irradiation on transformation of C3H 10T 1/2 cells.
Academic Article Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation.
Academic Article Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.
Academic Article RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.
Academic Article Loss of Nfkb1 leads to early onset aging.
Academic Article STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
Academic Article EPR oxygen images predict tumor control by a 50% tumor control radiation dose.
Academic Article Evidence for the Use of Multiple Mechanisms by Herpes Simplex Virus-1 R7020 to Inhibit Intimal Hyperplasia.
Academic Article Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein a Signaling.
Academic Article JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers.
Academic Article ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response.
Academic Article Rhythmic radiotherapy beats down TGF-ß.
Academic Article The AIM2 and NLRP3 inflammasomes trigger IL-1-mediated antitumor effects during radiation.
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